The image obtained by CRYO-TEM (Cryogenic Transmission Electron Microscopy), which allows direct observation of nanostructures in a near-native state, shows the nanostructures of the resveratrol-containing nanoemulsion sample. Spherical objects of varying sizes are visible, consistent with DLS analysis results. CRYO-TEM enables the assessment of morphology and nanoparticle distribution and complements the physicochemical analyses of the formulation.