Xanthohumol is a natural polyphenol derived from hops (Humulus lupulus). This R&D sample presents a liposomal nanoemulsion developed for the assessment of stability, physicochemical characteristics, and further optimization and implementation of innovative products for research and development and commercial applications.
Active Ingredient
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Particle Size (DLS)
Stability (Turbiscan)
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An advanced nanoemulsion formulation with 1% xanthohumol extract (>95%), developed as part of Liposome Factory’s research and development efforts. This sample is intended for evaluating the quality of the formulation and for further development and implementation work.
Dynamic Light Scattering (DLS) analysis showed an average nanoparticle size (Z-Average) of 48.21 nm with a polydispersity index (PdI) of 0.206. The result indicates a narrow particle size distribution and high formulation homogeneity. The measurement quality was rated as “Good,” confirming the reliability of the analysis.
Turbiscan analysis confirms the high physical stability of the xanthohumol nanoemulsion. Low TSI values and their slow increase over time indicate the absence of significant destabilization processes such as sedimentation, creaming, or particle aggregation.
The image obtained by CRYO-TEM (Cryogenic Transmission Electron Microscopy), which allows direct observation of nanostructures in a near-natural state, shows the nanostructures of the xanthohumol-containing nanoemulsion sample. Spherical objects of varying sizes are visible, consistent with DLS analysis results, which showed an average particle size of 48.21 nm (Z-Average). CRYO-TEM analysis enables the assessment of nanoparticle morphology and distribution and complements the physicochemical analyses of the formulation. The obtained results confirm the high quality and homogeneity of the developed nanoemulsion.
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